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Anti-IgE

Test Code: 2105
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Clinical and Procedure
Clinical Utility

This ELISA measures IgG antibodies specific for IgE. These autoantibodies have been implicated as a causative agent in autoimmune chronic urticaria. In addition, these autoantibodies have also been implicated as significant in atopic dermatitis and hyper IgE syndrome.

Procedure

IgG antibodies specific for IgE are detected with a solid phase indirect non-competitive ELISA. Human IgE is coated onto polystyrene micro-wells (solid-phase antigen). IgG antibodies in serum that bind to the IgE are detected with a labeled anti-human IgG antibody. This test has not been cleared or approved for diagnostic use by the U.S. Food and Drug Administration.

Turnaround Time

5-7 business days from receipt of specimen

Specimen Information
Specimen Type Test Code CPT Code NY Approved Volume Assay Range Special Instructions
serum 2105 83516 Yes

1 mL (min. 100 uL)

Resulted as Normal or Elevated. A result of normal indicates that the level of IgG anti-IgE antibodies is similar to that seen in a population of healthy individuals. A result of elevated indicates an increased level of IgG anti-IgE antibodies compared to healthy individuals.

  • Collect 1 mL of serum.
  • Blood should be collected and allowed to clot prior to centrifugation.
  • Ship at ambient temperature Monday through Friday.
  • If the specimen is to be held for more than two weeks, it should be stored frozen until shipped. 1 week ambient,
    2 weeks at 2-8 C, 4 weeks frozen at -20 C or below

Qualitative test resulted as Normal or Elevated. A result of normal indicates that the level of IgG anti-IgE antibodies is similar to that seen in a population of healthy individuals. A result of elevated indicates an increased level of IgG anti-IgE antibodies compared to healthy individuals.

Disclaimer

Specimens are approved for testing in New York only when indicated in the Specimen Information field above.

The CPT codes provided are based on Viracor Eurofins' interpretation of the American Medical Association's Current Procedural Terminology (CPT) codes and are provided for general informational purposes only. CPT coding is the sole responsibility of the billing party. Questions regarding coding should be addressed to your local Medicare carrier. Viracor Eurofins assumes no responsibility for billing errors due to reliance on the CPT codes illustrated in this material.

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