Cytokines have emerged as molecules of importance in the regulation of many immunologic processes in the cell. The ability to accurately measure quantitative and qualitative differences in cytokine production is becoming increasingly important to the understanding of normal and pathological processes. Visit our test menu to see the complete menu of cytokines available.
Viracor offers Pneumococcal Antibody Panels (23, 14, 12 and 7 serotypes) that are important for determining specific Streptococcus pneumoniae serotype IgG antibody concentrations (titers) in patients prior to and after pneumococcal vaccinations. In patients with recurrent bacterial infections, or in patients suspected to have primary or secondary immunodeficiencies, pneumococcal antibody titers may be useful to evaluate the protective status of a patient and to assess humoral immune function.10-15
Antibody avidity functions are another important determinant of protective efficacy against Streptococcus pneumoniae, and the ability to generate higher avidity antibodies is a key aspect of a fully functional immune system.1-4 The avidity of antibodies induced by a vaccine is an independent correlate of protection and is an important supplement to the measurement of pneumococcal IgG antibody concentration (titers).1-9 Viracor’s Pneumococcal Avidity Panels measure antibody avidity to serotypes found in the pneumococcal polysaccharide vaccine Pneumovax 23® (PPV) and the pneumococcal conjugated vaccine Prevnar 13® (PCV).
The capability for analysis of both cell surface and intracellular components has made flow cytometry a well-established and essential tool in medical diagnostics, as well as pharmaceutical and clinical research. The fields of immunology, transplantation, hematology, genetics, cancer and HIV have particularly benefited due to flow cytometry’s capabilities to detect many parameters from a single cell in a rapid, accurate, non-invasive manner. Viracor uses flow cytometry to provide you with:
The rapid expansion in flow cytometry applications allow the testing platform to play an even larger role in medicine and systems biology in the future.
Using multiplex array format with Meso Scale Discovery (MSD®) Sector Imager 2400, MSD Cytokine assays measure from one to ten cytokines in a 96 well MULTI-SPOT plate. The assay employs a sandwich immunoassay format. MSD technology uses electrochemiluminescence detection; a CCD camera allows for the quantification of light emitted from each spot in each well. MSD software generates a standard curve to determine sample cytokine concentrations.