Resource Center
BK Polyomavirus and thrombotic microangiopathy (TMA) are significant complications following stem cell transplantation, leading to serious health risks. In this presentation, Dr. Ben Laskin, Dr. Sonata Jodele, and Dr. Steve Kleiboeker discuss the current understanding of these conditions and highlight gaps in knowledge and treatment strategies. While advances have been made in diagnosing and managing BK virus-related complications, unmet needs remain in effectively addressing TMA. The presentation underscores the importance of continued research and collaboration to improve patient outcomes.
This bi-lateral lung transplant recipient is a 65 year-old male patient who received his lung transplant due to end-stage lung disease secondary to non-CF bronchiectasis. The donor and recipient CMV serostatus is D+/R+. The patient’s initial peri-operative course was complicated by difficult explant, primary graft dysfunction, respiratory failure requiring prolonged mechanical ventilation, renal insufficiency and recurrent infectious concerns, including pseudomonas and stenotrophomonas pneumonias.